September 2020 Table of Contents

Outcomes Research

Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Binational Analysis Derived From the United Kingdom and United States

Vinayak Nagaraja, MBBS, MS, MMed (Clin Epi), FRACP*; Muhammad Rashid, MD*; David L. Fischmann, MD; H. Vernon Anderson, MD; Tim Kinnaird, MD; Peter Ludman, MD; Samir R. Kapadia, MD; Randall C. Starling, MD; Chadi Alraies, MD; Chun Shing Kwok, MBBS, PhD, MSc, BSc, MRCP(UK); Mohamed O. Mohamed, MD; Nick Curzen, MD; Mamas A. Mamas, DPhil            *Joint first authors

This study aims to compare and contrast the indications, clinical and procedural characteristics, and periprocedural outcomes of patients with cardiac transplant undergoing percutaneous coronary intervention in the United States and United Kingdom.

J INVASIVE CARDIOL 2020;32(9):321-329.

Transcatheter Aortic Valve Replacement 

Transcatheter Aortic Valve Replacement Without the Use of Contrast Medium: An Alternative Safe Implantation Technique

Tamer Owais, MD*; Mohammad El Garhy, MD*; Jürgen Fuchs, MD; Mathias Schreiber, MD; Evaldas Girdauskas, MD; Thomas Kuntze, MD                *Joint first authors

New transcatheter equipment and accumulated experience have stimulated further refinements in implantation techniques. We aimed to compare the outcomes of transfemoral transcatheter aortic valve replacement with and without the use of contrast medium in patients with glomerular filtration rate <30 mL/min/1.73 m2

J INVASIVE CARDIOL 2020;32(9):330-334. Epub 2020 May 20. 

Coronary Artery Disease

Effect of Preloading With High Dose of Rosuvastatin on Serum Levels of Inflammatory Markers After Percutaneous Coronary Intervention 

Juliano R. Slhessarenko, MD; Mario Hirata, PhD; Amanda Sousa, MD, PhD; Gisele M. Bastos, PhD; Elisa M.S. Higa, PhD; Margareth G. Mouro, BS; Guilherme C. Sobrera, MS; Renata D. Slhessarenko, PhD; Renata Viana, MD; Alexandre Abizaid, MD, PhD; J. Ribamar Costa Jr, MD, PhD

We sought to assess the effects of a high loading dose of rosuvastatin (40 mg) on acute inflammatory response after coronary stenting. The primary goal was a comparison in the variation of the serum inflammatory markers and their gene expression at three different time points in 125 patients randomized to treatment with or without rosuvastatin. 

J INVASIVE CARDIOL 2020;32(9):335-341. Epub 2020 June 22.

Coronary Artery Disease

A Sex-Based Analysis From the RAIN-CARDIOGROUP VII Study (VeRy Thin Stents for Patients With Left MAIn or BifurcatioN in Real Life) on Left Main Stenting

Daniela Trabattoni, MD; Sebastiano Gili, MD; Giovanni Teruzzi, MD; Pierluigi Omedè, MD; Enrico Cerrato, MD; Christian Templin, MD; Davide Capodanno, MD; Thomas Lüscher, MD; Nicola Ryan, MD; Giuseppe Venuti, MD; Andrea Montabone, MD; Wojciech Wojakowski, MD; Andrea Rognoni, MD; Gerard Helft, MD; Diego Gallo, PhD; Carlo Alberto Biolè, MD; Radoslaw Parma, MD; Leonardo De Luca, MD; Filippo Figini, MD; Satoru Mitomo, MD; Alessio Mattesini, MD; Giacomo Boccuzzi, MD; Giorgio Quadri, MD; Wojciech Wa´nha, MD; Grzegorz Smolka, MD; Zenon Huczek, MD; Alaide Chieffo, MD; Ivan Nuñez-Gil, MD; Umberto Morbiducci, MD; Mario Iannaccone, MD; Carlo di Mario, MD; Claudio Moretti, MD; Maurizio D’Amico, MD; Imad Sheiban, MD; Javier Escaned, MD; Fabrizio D’Ascenzo, MD

There is a lack of data on clinical outcomes of percutaneous coronary intervention with ultrathin stents on unprotected left main coronary artery comparing women and men. In our study, all patients treated with unprotected left main percutaneous coronary intervention with ultrathin stents (struts ≤81 µm) enrolled in the RAIN-CARDIOGROUP VII study were analyzed according to a sex-assessment evaluation. 

J INVASIVE CARDIOL 2020;32(9):342-346. Epub 2020 June 22.

Transcatheter Aortic Valve Replacement 

Predicting the Need For Permanent Pacing After Implantation of the Repositionable Lotus

Roly Hilling-Smith, MD; Tiffany Kemp, MD; Maureen Dooley, MD; Rajiv Rampat, MD; Adam de Belder, MD; Andrew Hill, MD; James Cockburn, MD; Uday Trivedi, MD; David Hildick-Smith, MD; Michele Homsy, MD

Permanent pacemaker implantation rates vary according to type of transcatheter aortic valve implantation (TAVI) device, implantation technique, and patient-related factors. We analyzed the baseline characteristics, and then the preprocedure and daily postprocedure electrocardiograms of 101 consecutive patients who underwent TAVI using the Lotus valve (Boston Scientific) between 2013 and 2015. 

J INVASIVE CARDIOL 2020;32(9):347-349. Epub 2020 July 10.

Chronic Total Occlusion

Clinical Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Native Coronary Arteries vs Saphenous Vein Grafts 

Ahmad Shoaib, MD; Thomas W. Johnson, MD; Adrian Banning, MD; Peter Ludman, MD; Muhammad Rashid, PhD; Jessica Potts, PhD; Chun Shing Kwok, MBBS, PhD, MSc, BSc, MRCP(UK); Evan Kontopantelis, PhD; Ziyad A. Azam, MBChB; Tim Kinnaird, MD; Mamas A. Mamas, DPhil

There are limited data comparing outcomes of patients with previous coronary artery bypass grafting presenting with stable angina who undergo percutaneous coronary intervention to either a saphenous vein graft or a chronic total occlusion in the native coronary arteries. We compared the outcomes of these two groups in a national cohort. 

J INVASIVE CARDIOL 2020;32(9):350-357. Epub 2020 August 10. 

Left Atrial Appendage Closure

Evaluation of Effectiveness and Safety of Left Atrial Appendage Closure Under Moderate Conscious Sedation

Ismail Ates, MD; Konstantinos Marmagkiolis, MD; Gulcan Kose, MD; Cezar Iliescu, MD; Mehmet Cilingiroglu, MD

Left atrial appendage closure (LAAC) using the Watchman device has become a well-established therapeutic alternative to oral anticoagulation in high-risk patients for bleeding with paroxysmal, persistent atrial fibrillation (Afib) or permanent Afib. Currently, in the United States, LAAC is performed under general anesthesia. We present the feasibility, effectiveness, and safety of LAAC under moderate conscious sedation. 

J INVASIVE CARDIOL 2020;32(9):358-362. Epub 2020 June 8.

Brief Communication 

Use of MitraClip to Target Obstructive SAM in Severe Diffuse-Type Hypertrophic Cardiomyopathy: Case Report and Review of Literature

Ashleigh Long, MD, PhD and Paul Mahoney, MD

Hypertrophic cardiomyopathy (HCM) is frequently associated with abnormalities of the mitral valve; these commonly include systolic anterior motion of anterior mitral leaflets that contribute to dynamic left ventricular outflow tract obstruction and secondary mitral regurgitation. We describe the successful non-surgical catheter-based management of a 72-year-old woman at high surgical risk and review current management strategies for HCM.

J INVASIVE CARDIOL 2020;32(9):E228-E232.

Brief Communication 

Right Heart Catheterization: Right From the Anatomical Snuffbox

Hady Lichaa, MD 

We present two cases where a right heart catheterization was performed from the anatomical snuffbox through the distal cephalic vein along with a left heart catheterization from the distal radial artery. 

J INVASIVE CARDIOL 2020;32(9):E233-E237. 


Distal Transradial Access (dTRA) for Coronary Angiography and Interventions: A Quality Improvement Step Forward?

Marcos Danillo P. Oliveira, MD and Adriano Caixeta, MD, PhD

Distal TRA is a novel access site in the interventional cardiology field, with current data demonstrating high success and infrequent complication rates — global procedural metrics that are comparable with historical proximal TRA. Distal TRA may conversely provide important advantages over proximal TRA, including patient comfort, shorter hemostasis time, and lower radial artery occlusion rates.

J INVASIVE CARDIOL 2020;32(9):E238-E239. 

Clinical Images 

Prinzmetal Angina Mimicking Severe Three-Vessel Coronary Artery Disease

Ziad Dahdouh, MD and Tahir Mohamed, MD

Coronary artery vasospasm, or Prinzmetal angina, remains a challenging diagnosis. Prinzmetal angina usually affects only one coronary vessel; however, in this case, it occurred simultaneously in three coronary arteries, and was totally relieved after nitrate administration.

J INVASIVE CARDIOL 2020;32(9):E240-E241. 

Clinical Images 

Percutaneous Closure of a “Doughnut Leak” Around an Atrial Septal Occluder Device in a Patient With Recurrent Migraines

Pradyumna Agasthi, MD; Joseph N. Graziano, MD; Stephen G. Pophal, MD

A 10-year-old girl with pulmonary atresia status post transannular patch repair and secundum atrial septal defect (ASD) underwent percutaneous ASD closure 5 years earlier. There was improvement in arterial saturation from 86% to 98% with minimal residual right-to-left shunt. Despite subsequent medical therapy, she developed recurrent migraines, which led us to pursue percutaneous closure of the shunt.

J INVASIVE CARDIOL 2020;32(9):E242-E243. 

Clinical Images 

An Ace Angiographic Diagnosis

Holly Morgan, MBBCh, MRCP; James Cullen, MD, FRCP; David Turpie, MBChB, MRCP, BSc

Interventional cardiologists should maintain awareness of extracardiac structures when undertaking cardiac catheterization, as pathology outside of the coronary arteries may be identified.

J INVASIVE CARDIOL 2020;32(9):E244-E245. 

Clinical Images 

Challenging Case of Percutaneous Closure of Right Coronary Artery to Right Atrial Fistula 

Pradyumna Agasthi, MD and Joseph N. Graziano, MD

We demonstrate the percutaneous closure of a coronary fistula and subsequent utilization of a vascular plug in a patient with challenging anatomy.

J INVASIVE CARDIOL 2020;32(9):E246-E247. 

Clinical Images 

Endothelialization of a Venous Stent at 1-month Post-Implantation: First in Human Angioscopic Assessment

Yasuhiro Tanabe, MD, PhD; Takanobu Mitarai, MD; Yuki Ishibashi, MD, PhD; Takumi Higuma, MD, PhD; Yoshihiro J. Akashi, MD, PhD

This is the first report to evaluate endothelialization in vivo; the evidence of endothelialization on the venous stent in the early phase suggests that antithrombotic therapy could be stopped in some patients with high risk of bleeding in the chronic phase.

J INVASIVE CARDIOL 2020;32(9):E248.

Clinical Images 

Conservative Management of Spontaneous Coronary Artery Dissection

Giovanni Lorenzoni, MD; Pierluigi Merella, MD; Stefano Bandino, MD; Graziana Viola, MD; Gavino Casu, MD

Spontaneous coronary artery dissection (SCAD) is caused by separation of the vessel wall and hematoma development. We demonstrate that SCAD often resolves spontaneously, with an average period of 35 days from the event usually sufficient to demonstrate angiographic healing.

J INVASIVE CARDIOL 2020;32(9):E249.