September 2007

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Volume 19 Issue 9
Despite meta-analyses showing either similar rates or only slightly increased rates of stent thrombosis in patients with a drug-eluting stent (DES),1–5 clinicians remain concerned about the risk of late stent thrombosis in these patients. It is a unc…
During the fourth week of gestation, the primitive atrium divides into right and left atria by forming two septa, the septum primum and secundum. As the septum primum grows from the dorsocranial wall, two openings develop, the foramen primum at the l…
Percutaneous revascularization of diseased saphenous vein bypass grafts (SVGs) remains a difficult challenge for the interventional cardiologist despite major advances in catheter-based reperfusion therapies, adjunctive pharmacology and stent technol…
Stent thrombosis is rare, but very serious, with potentially fatal consequences following percutaneous coronary intervention (PCI). Traditionally, it has been classified as acute, within 48 hours, subacute up to 30 days, and late, corresponding to al…
Coronary angiography in the early phase of ST-elevation acute myocardial infarction (STEMI) usually identifies total thrombotic occlusion of a single infarct-related artery.1 However, simultaneous acute occlusion of all major epicardial coronary arte…
Treating chronic total occlusions (CTOs) remains one of the major challenges in interventional cardiology. In the last 20 years, as the procedural outcomes of intervention for CTOs have significantly increased as a function of improved guidewires and…
Coronary arterial anomalies occur in approximately 1% of the population, without other congenital cardiac malformations.1 The incidence of anomalous origin of the right coronary artery out of the right sinus of Valsalva ranges from under 0.01–0.09%.…
Successful recanalization of chronic total occlusion (CTO) improves left ventricular function1 and survival.2 There are, however, several difficulties with percutaneous coronary intervention (PCI) for CTO (CTOPCI). Failure to cross the occlusive lesi…
The aorto-ostial junction has high elastic fiber content with significant elastic recoil.1-7 Ostial left main coronary artery (LMCA) stenoses have larger lumen areas with less plaque burden and more negative remodeling than non-ostial LMCA stenoses.…
Despite advances in percutaneous coronary intervention techniques over the last two decades, the unprotected left main has largely remained the domain of cardiovascular surgery. The subset of patients with left main disease in the Collaborative Study…