July 2007

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Volume 19 Issue 7
Coronary artery fistulae are uncommon vascular anomalies. The incidence of these anomalies is low, ranging from 0.2 to 0.25%.1 The fistulae frequently drain into one of the ventricles, the pulmonary arteries, the coronary sinus and the superior vena…
Patent ductus arteriosus (PDA) may be an isolated lesion or may be present in association with other defects. Isolated PDA constitutes 6–11% of all congenital heart defects. The configuration of PDA varies considerably, but most often it has a conica…
Although stenting has improved clinical outcomes of patients undergoing percutaneous coronary intervention (PCI), bare-metal stents are associated with a considerable risk of restenosis.1,2 The main cause of in-stent restenosis is excessive neointima…
Interatrial septal defects (IASD) have been associated with an increased incidence of cryptogenic strokes.1–7 Percutaneous closure of these defects is now widely performed and the safety of this procedure has been established. It is unclear, however,…
Introduction of drug-eluting stent (DES) has led to a marked reduction in the problem of in-stent restenosis across all patient subsets and lesions complexities.7 Recently, several case reports of aneurysm formation after DES implantation have been r…
Variant angina is a distinct clinical entity first described by Prinzmetal and associates in 1959.1 The classic presentation is characterized by chest pain occurring at rest, and is more frequent in young women. Unlike true angina, the chest pain in…
Rupture of atherosclerotic plaque leading to exposure of highly thrombogenic material to the blood pool with subsequent thrombus formation is the principal mechanism associated with acute coronary syndromes.1,2 Percutaneous coronary intervention (PCI…
When clopidogrel is added to background aspirin therapy, it reduces the composite of cardiovascular death, myocardial infarction (MI) or stroke in patients with acute coronary syndromes (ACS)1 or percutaneous revascularization.2 The most consistent r…
Conflicting opinions exist regarding the optimal dose of acetyl salicylic acid (ASA) to be given after percutaneous coronary intervention (PCI) with drug-eluting stents (DES). The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy sug…
Patent ductus arteriosus (PDA) can cause congestive cardiac failure, repeated pneumonia, pulmonary hypertension and an increased risk for endocarditis. Transcatheter closure of PDA is currently the preferred therapeutic alternative to surgical ligati…