2019 Top Ten

2019 Top Ten • Journal of Invasive Cardiology • Vol. 31

Peripheral Vascular Disease

Clinical Outcomes and Cost Comparisons of Stent and Non-Stent Interventions in Infrainguinal Peripheral Artery Disease: Insights From the Excellence in Peripheral Artery Disease (XLPAD) Registry

Subhash Banerjee, MD;  Haekyung Jeon-Slaughter, PhD;  Ehrin J. Armstrong, MD, MSc;  Christopher Bajzer, MD; Mazen Abu-Fadel, MD;  Houman Khalili, MD;  Anand Prasad, MD;  Bassel Bau Dargham, MD; Preeti Kamath, BDS, MHA;  Tayo Addo, MD;  Michael Luna, MD;  Osvaldo Gigliotti, MD;  Mazin Foteh, MD; Ian Cawich, MD;  Scott Kinlay, MD;  Mujtaba Ali, MD;  Bala Ramanan, MD;  Khusrow Niazi, MD;  Shirling Tsai, MD;  Nicolas W. Shammas, MD;  Emmanouil S. Brilakis, MD, PhD

The contemporary limb outcomes and costs of stent-based vs non-stent based strategies in endovascular revascularization of femoropopliteal (FP) peripheral artery disease are not well understood. We present data from the ongoing US multicenter Excellence in Peripheral Artery Disease Registry between 2006-2016 to compare stent vs non-stent treatment outcomes and associated costs in FP interventions.

J INVASIVE CARDIOL 2019:31(1):1-9.

Coronary Artery Disease

A Cancer Paradox: Machine-Learning Backed Propensity-Score Analysis of Coronary Angiography Findings in Cardio-Oncology

Dinu Valentin Balanescu, MD*;  Dominique J Monlezun, MD*;  Teodora Donisan, MD;  David Boone, MD; Frances Cervoni-Curet, MD;  Nicolas Palaskas, MD;  Juan Lopez-Mattei, MD;  Peter Kim, MD;  Cezar Iliescu, MD; Serban Mihai Balanescu, MD       *Joint first authors.

Cancer has been proposed as a cardiovascular risk factor. We aimed to assess the cardiovascular risk profile and coronary angiography findings of cancer patients and compare them to those of patients without cancer. 

J INVASIVE CARDIOL 2019:31(1):21-26.

Coronary Artery Disease

Comparison Between Traditional and Guide-Catheter Extension Reverse Controlled Antegrade Dissection and Retrograde Tracking: Insights From the PROGRESS-CTO Registry 

Iosif Xenogiannis, MD;  Dimitri Karmpaliotis, MD2;  Khaldoon Alaswad, MD;  Farouc A. Jaffer, MD, PhD; Robert W. Yeh, MD;  Mitul Patel, MD6;  Ehtisham Mahmud, MD;  James W. Choi, MD;  M. Nicholas Burke, MD; Anthony H. Doing, MD;  Phil Dattilo, MD;  Catalin Toma, MD;  A.J. Conrad Smith, MD;  Barry Uretsky, MD;  Oleg Krestyaninov, MD;  Dmitrii Khelimskii, MD;  Elizabeth Holper, MD;  Srinivasa Potluri, MD; R. Michael Wyman, MD;  David E. Kandzari, MD;  Santiago Garcia, MD;  Michalis Koutouzis, MD; Ioannis Tsiafoutis, MD;  Wissam Jaber, MD;  Habib Samady, MD; Jeffrey W. Moses, MD; Nicholas J. Lembo, MD; Manish Parikh, MD;  Ajay J. Kirtane, MD;  Ziad A. Ali, MD;  Darshan Doshi, MD;  Peter Tajti, MD; Bavana V. Rangan, BDS, MPH;  Shuaib Abdullah, MD;  Subhash Banerjee, MD;  Emmanouil S. Brilakis, MD, PhD

The most common re-entry technique during retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is reverse controlled antegrade and retrograde tracking (rCART). The use of guide-catheter extensions can facilitate rCART, but has received limited study. We compared the clinical and procedural characteristics and outcomes of traditional rCART vs guide-catheter extension rCART vs cases in which both techniques were used (combined rCART) in patients with successful retrograde CTO crossing in a contemporary multicenter CTO-PCI registry. 

J INVASIVE CARDIOL 2019;31(1):27-34. (Epub 2018 November 11).

Coronary Artery Disease 

The Spontaneous Coronary Slow-Flow Phenomenon: Reversal by Intracoronary Nicardipine

Hetal H. Mehta, MD;  Mackenzie Morris, MD;  David L. Fischman, MD;  John J. Finley, IV, MD;  Nicholas Ruggiero, MD;  Paul Walinsky, MD;  Melissa McCarey, MPH;  Michael P. Savage, MD

An under-recognized cause of chest pain, the coronary slow-flow (CSF) phenomenon is characterized by delayed coronary opacification during diagnostic angiography in the absence of epicardial coronary artery disease. Given its angiographic resemblance to no-reflow, a condition responsive to calcium-channel blockers, we hypothesized that spontaneous CSF may similarly be reversed by intracoronary (IC) nicardipine; this theory was evaluated in 30 patients. 

J INVASIVE CARDIOL 2019;31(3):42-45.

Coronary Artery Disease

Shockwave Intravascular Lithotripsy for Calcified Coronary Lesions: First Real-World Experience 

Bernard Wong, MBChB;  Seif El-Jack, MBBS;  Ruth Newcombe;  Timothy Glenie, MBChB;  Guy Armstrong, MBChB;  Ali Khan, MBBS

Calcified coronary lesions often cause suboptimal stent expansion, which is one of the greatest predictors of adverse outcomes such as stent thrombosis and restenosis. Shockwave intravascular lithotripsy (S-IVL; Shockwave Medical, Inc) is a recently approved technique used in the treatment of heavily calcified coronary lesions. We present our early real-world experience with the S-IVL device in 26 patients. 

J INVASIVE CARDIOL 2019;31(3):46-48.

Practice Management

Sleep Deprivation in Cardiology: A Multidisciplinary Survey

Angie S. Lobo, MD;  Yader Sandoval, MD;  M. Nicholas Burke, MD;  Paul Sorajja, MD;  Michael Mooney, MD;  Jay Traverse, MD;  Timothy D. Henry, MD;  Ivan Chavez, MD;  Mario Gössl, MD;  Daniel L. Lips, MD;  Steven M. Bradley, MD;  Anil Poulose, MD;  Yale Wang, MD;  Emmanouil S. Brilakis, MD, PhD

The burden and impact of sleep deprivation on cardiology have received limited study. Our multidisciplinary, online survey provides insights into sleep health patterns among cardiovascular workers and potential factors contributing to sleep deprivation.

J INVASIVE CARDIOL 2019;31(6):195-198. Epub 2019 April 15.


Ultrasound Guidance in Femoral Artery Catheterization: A Systematic Review and a Meta-Analysis of Randomized Controlled Trials

Mohammed K. Rashid, MD;  Nazanin Sahami, MD;  Kuljit Singh, MD, PhD;  Jose Winter, MD;  Tej Sheth, MD;  Sanjit S. Jolly, MD, MSc, FRCP

During percutaneous cardiac procedures, the use of radial access is growing, but femoral access remains needed for large-bore, high-risk procedures. Methods are needed to make femoral access safer. In this systematic review and meta-analysis of randomized-controlled trials, we assessed whether ultrasound guidance was associated with a decreased risk of vascular complications during femoral artery catheterization.

J INVASIVE CARDIOL 2019;31(7):E192-E198.

Imaging Techniques 

Optimal Technique for Performing Invasive Pulmonary Angiography for Chronic Thromboembolic Pulmonary Disease

Lawrence Ang, MD;  Anna McDivit Mizzell, MD;  Lori B. Daniels, MD, MAS;  Ori Ben-Yehuda, MD;  Ehtisham Mahmud, MD

This article provides detailed guidance in performing hemodynamic assessment and invasive pulmonary angiography for the evaluation of chronic thromboembolic pulmonary disease.

J INVASIVE CARDIOL 2019;31(7):E211-E219.

Coronary Artery Disease

The Dose and Timing of Fentanyl Impacts on Ticagrelor Absorption and Platelet Inhibition During Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial

Rakesh R. Goli, BA;  Khalil Ibrahim, MD;  Rohan Shah, MD;  Thomas S. Kickler, MD;  William A. Clarke, PhD;  Jon R. Resar, MD;  Steven P. Schulman, MD;  John W. McEvoy, MBBCh, MHS

In this secondary analysis of the PACIFY randomized trial, we assessed whether dose and timing of fentanyl have implications for the pharmacokinetics and pharmacodynamics of ticagrelor loading during PCI. We have previously shown that fentanyl slows absorption of oral ticagrelor, attenuating its effect on platelet inhibition. We now demonstrate that this mechanism appears to be dose- and time-dependent.

J INVASIVE CARDIOL 2019;31(9):265-271. 

Coronary Artery Disease

Dedicated Bifurcation Stents for Coronary Bifurcation Lesions: A Systematic Review and Meta Analysis of Randomized-Controlled Trials

Mohamed O. Mohamed, MBBCh, MRCP(UK);  Mamas A. Mamas, BMBCh, DPhil, MRCP;  Vinayak Nagaraja, MBBS, MS,  MMed (ClinEpi), FRACP;  M. Chadi Alraies, MD;  Pablo Lamelas, MD, MSc;  Nikolaos Tzemos, MD;  Diana Ayan, MSc;  Shahar Lavi, MD;  Rodrigo Bagur, MD, PhD

Percutaneous coronary intervention (PCI) of coronary bifurcation lesions (CBL) remains a challenge in contemporary practice due to the procedural and technical difficulties involved. We sought to review the current evidence on the safety and clinical outcomes of dedicated bifurcation stent (DBS) implantation in comparison with established treatment strategies for CBL-PCI. We therefore conducted a comprehensive search to identify randomized control trials reporting 1-year clinical and angiographic outcomes of patients undergoing CBL-PCI with DBS vs conventional CBL-PCI strategies. A total of 5 RCTs comprising 1249 participants met the inclusion criteria. The present analysis suggests that CBL-PCI with DBS may be associated with similar 1-year clinical and angiographic outcomes compared with conventional CBL-PCI strategies. However, the low quality of evidence and limited follow-up warrant further studies. 

J INVASIVE CARDIOL 2019;31(12):E344-E355.