Volume 19 - Issue 10 - October, 2007

“Fogarty-Like” Removal of Large Coronary Thrombus

In patients undergoing emergency percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI), several thrombectomy and distal protection devices have been evaluated in order to either remove thrombus and plaque components at the occlusion site, or trap embolic materials, respectively. The effect of thrombectomy devices on myocardial perfusion have been conflicting: some studies1–3 show a benefit, while others suggest a detrimental effect on myocardial salvage resulting in increased infarct size.4 Specifically, unrestricted use of dista

Outcomes of Primary Percutaneous Coronary Intervention at a Joint Commission International Accredited Hospital in a Developing

Percutaneous coronary intervention (PCI) is an established therapy for patients with symptomatic coronary artery disease including acute coronary syndromes. In patients presenting with ST-elevation myocardial infarction (STEMI), a considerable body of evidence now suggests that reperfusion with primary PCI provides better short- and long-term outcomes compared to fibrinolytic therapy.1-3 Although widely adopted as the default strategy for patients presenting with STEMI in developed nations, there are virtually no data on the applicability, success and outcomes of primary PCI in t

Rare Case of Persistent Left Superior Vena Cava to Left Upper Pulmonary Vein: Pathway for Paradoxical Embolization and Develop

The performance of transesophageal echocardiography (TEE) has become common in the routine assessment of patients who have had transient ischemic attacks (TIAs) or stroke. As part of the TEE evaluation, agitated saline is usually injected through a peripheral intravenous (IV) line after which a Valsalva maneuver is performed to determine the presence or absence of right-to-left shunting across a patent foramen ovale (PFO). In our patient, a large volume of microbubbles was first seen in the left atrium. On careful review of the TEE, microbubbles were observed entering the left atrium throug

Assessing Intermediate Coronary Lesions: Angiographic Prediction of Lesion Severity on Intravascular Ultrasound

Conventional angiography is the gold standard in clinical practice for diagnosing atherosclerotic compromise of the coronary artery tree. However, coronary angiography has several known limitations, including a lack of correlation between the percentage of stenosis and the lesion’s physiologic importance1 and considerable interobserver variability in classifying the lesion’s severity.2,3

Intravascular ultrasound (IVUS) has been shown to detect atherosclerotic compromise that cannot be detected by conventional angiography.4 Using tomographi

Adenosine Conditioning and Pacing in Conjunction with Early Intra-Aortic Balloon Pump Use and Glycoprotein IIb/IIIa Inhibition

Cardiogenic shock complicating myocardial infarction carries a poor prognosis. Data regarding percutaneous intervention in the very elderly with cardiogenic shock is sparse.1 Age is an independent risk factor for worse outcome with cardiogenic shock.1 Few studies or registries include the very elderly with cardiogenic shock.2,3 Improved TIMI (Thrombolysis In Myocardial Infarction) flow post-intervention provides a better outcome in this condition.4 Multivessel intervention is also independently prognostic of a worse outcome in cardiogenic shock.

Utility of Sirolimus-Eluting Cypher™ Stents to Reduce 12-Month Target Vessel Revascularization in Saphenous Vein Graft Stenoses

Approximately 1 million patients are now treated annually in the United States with drug-eluting stents (DES). Usage of these stents is substantiated in many patient and lesion subsets by their documented relative safety and reduction in clinical restenosis in large-scale randomized clinical trials.1,2 Such trials cannot be feasibly performed in all groups of patients. The pathology of atherosclerosis in saphenous vein grafts (SVGs) differs somewhat from that in native coronary arteries, and restenosis after bare-metal stenting (BMS) tends to occur more frequently in the former t

Late Coronary Stent Infection: A Unique Complication after Drug-Eluting Stent Implantation

Coronary stent infection is a rare but previously reported complication of coronary artery stenting procedures (CAS).1–13 In the few cases reported in the literature, patients have presented within days to weeks of stent implantation with fever, and the infection presumably was related to periprocedural bacteremia or direct septic stent implantation.14–18

Case Report. A 75-year-old male was seen for stable angina pectoris in June 2005. His past medical history included hypertension, type II diabetes mellitus, hypercholesterolemia

DES for SVG Stenosis — We All Want to Do It, But Are We There Yet?

More than 400,000 coronary artery bypass graft (CABG) operations are performed annually in the United States, with the saphenous vein graft (SVG) as the major type of conduit.1 However, surgical revascularization is not definitive, and recurrent angina occurs in 5–10% of patients per year.2 While progression of native coronary atherosclerosis explains some of the symptom recurrence, disease of the grafts is a major problem — over 50% of SVGs are severely diseased or occluded after 10 years.3,4 Because re-do CABG is associated with significant mor

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