Volume 17 - Issue 11 - November, 2005

Myonecrosis after Elective Percutaneous Coronary Intervention: Effect of Clopidogrel-Statin Interaction

Sadi Gulec, MD, Cagdas Ozdol, MD, Uzeyir Rahimov, MD, Yusuf Atmaca, MD, Deniz Kumbasar, MD, Cetin Erol, MD

Myocardial injury after percutaneous coronary interventions has been recognized as a frequent and prognostically important event.1 Multiple institutions have now reported follow-up studies of percutaneous revascularization, and the evidence supports a relation between the elevation of cardiac enzymes and poorer clinical outcomes during subsequent clinical evaluations.1–4 Recent studies presented evidence that statin therapy before percutaneous coronary interventions (PCI) is associated with a marked improvement in short- and long-term prognosis.5,6 Reduction ...

Safety and Efficacy of a Multipurpose Coronary Angiography Strategy Using the Transradial Technique

Marcelo Sanmartin, MD, José Esparza, MD, Joaquin Moxica, MD, José Antonio Baz, MD, Andréas Iñiguez-Romo, MD

Transradial coronary percutaneous procedures are associated with reduced entry site complications compared to transfemoral or transbrachial techniques.1–4 However, the transradial approach is technically more challenging and time-consuming,4 which explains its less widespread acceptance as compared to the transfemoral approach. Nonetheless, over the past ten years, considerable improvements have been achieved in catheter configuration and design, and a great variety of transradial-dedicated material is now available. The availability of specifically designed arterial sh...

Poor Outcome in Patients Treated with Brachytherapy for Diffuse In-Stent Restenosis. The Role of Additional Stenting Despite Pro

Dennis Zavalloni, MD, Marco Rossi, MD, Guido Belli, MD, Melania Scatturin, MD, Emanuela Morenghi, PhD, Federica Marsico, MD, Giampiero Catalano, MD, Giovanni Tosi, MD, Paolo Pagnotta, MD, Patrizia Presbitero, MD

The recurrence of coronary in-stent restenosis has been significantly reduced by brachytherapy.1–3 Patients treated with brachytherapy are characterized by poor outcomes in concomitant stent deployment, mainly because of late vessel thrombosis.1,2,4 In the treatment of in-stent restenosis, additional stents may be required for either suboptimal results or residual flow-limiting dissections.5,6 The risk of late vessel thrombosis has been overcome by prolongation of double antiplatelet therapy,7 however specific studies focusing on the influence of ...

Coronary Artery Perforation During Percutaneous Coronary Intervention: Incidence and Outcomes in the New Interventional Era

Ravi K. Ramana, DO, Dinesh Arab, MD, Dominique Joyal, MD, Lowell Steen, MD, Leslie Cho, MD, Bruce Lewis, MD, Jayson Liu, MD, Henry Loeb, MD, Ferdinand Leya, MD

Coronary artery perforation (CP) is a rare and potentially life-threatening complication of percutaneous coronary intervention (PCI). CP has historically been reported to occur in 0.1–3.0% of PCI procedures.1–5 Although CP can be caused by coronary wires and balloon angioplasty,6 they are more frequently reported in PCI using atheroablative devices, stenting and excimer laser coronary angioplasty.2
In coronary artery perforations, the vessel damage may range from vessel puncture by the coronary wire, resulting in minimal dye staining to vessel rupture, fol...

Coronary Perforation 2006 — Watch for the Wire

Ariel Roguin MD, PhD and Rafael Beyar MD, DSc

The number of percutaneous coronary interventions (PCI) performed worldwide is increasing. With the improvement of technology and interventional tools, the number of procedures is expected to further increase. As the range of equipment available to the interventional cardiologist evolves, together with necessary operator expertise, not only will the number of procedures increase, but interventionists will be treating patients with complex disease and more challenging coronary anatomy.
Among the most dreadful complications seen during PCI are abrupt vessel closure and perforations. Improveme...

Failure of the Symbiot PTFE-Covered Stent to Reduce Distal Embolization During Percutaneous Coronary Intervention in Saphenous V

Daniel J. Blackman, MD, Robin P. Choudhury, MD, Adrian P. Banning, MD, Keith M. Channon, MD

Within a decade of coronary artery bypass graft surgery, 50% of saphenous vein grafts fail, causing recurrent angina and acute coronary syndromes.1 Because of the substantial risk associated with re-operation, percutaneous intervention is often preferred to further surgery in this population. However, percutaneous revascularization is hampered by a high incidence of acute complications, specifically, distal embolization and periprocedural myocardial infarction (MI).2,3 Significant elevation in cardiac enzymes resulting from distal embolization is an independent predictor ...

Use of Endovascular Stents for the Treatment of Coarctation of the Aorta in Children and Adults: Immediate and Midterm Results

Lisa Shah, MD, Ziyad Hijazi, MD, Satindir Sandhu, MD, Annette Joseph*, RN, Qi-Ling Cao, MD

Coarctation of the aorta (CoA) accounts for 6–8% of all forms of congenital heart defects. In children and adults, balloon angioplasty has become the preferred treatment for patients with recurrent CoA.1–5,6–18 The application of this technique for treatment of native coarctation is somewhat controversial due to the high incidence of recoarctation (5–10%) and the incidence of aneurysm formation (5–7%).7 There are few reports in the medical literature documenting the beneficial use of stent implantation for the treatment of CoA.2–5,8–10,19 Stent im...

Rescue Percutaneous Coronary Intervention: A Review

Umesh K. Arora, MD and Meeney Dhir, MD

The primary goal of therapy for acute myocardial infarction (AMI) is rapid, complete and sustained restoration of infarct-related artery (IRA) blood flow and myocardial perfusion, with a consequent positive impact on the patient’s outcome. Both fibrinolytic and mechanical restoration of anterograde coronary blood flow in patients suffering AMI have shown to improve left ventricular function, reduce infarct size and reduce mortality.1–10 The benefits of myocardial reperfusion, including the prevention of infarct expansion and improvement of electrical stability, are amplified whe...

The “Zipper” Lesion: A Rare but Serious Guiding Catheter-Induced Complication of a PCI Procedure

Stéphane Cook, MD and David Tueller, MD

A 42-year-old man presented with heavy chest pain of four hours’ duration. Physical examination was unremarkable. The ECG showed an acute septoapical infarction. Nitroglycerin, aspirin, clopidogrel and heparin were administered, and an emergency coronary angiography was performed from the right femoral artery (Figures 1 A and B). The left anterior descending artery was occluded distally. The left main trunk ostium was deeply intubated by a slightly too large Q4 6 French intervention catheter. There was, however, no damping or ventriculization of pressure. The occlusion was crossed with a ...

Transcatheter Fenestration of Autologous Pericardial Extracardiac Fontan via the Transhepatic Approach

Michael R. Recto, MD, Walter L. Sobczyk, MD, Erle H. Austin III, MD

The Fontan operation was first described for management of univentricular heart disease in 1971. Since it was first described, there have been several modifications to the original operation.1 In 1988, de Laval2 first proposed the concept of total cavopulmonary anastomosis (construction of an intra-atrial lateral tunnel to connect the inferior vena cava to the pulmonary artery together with a bidirectional cavopulmonary shunt) as an alternative to atriopulmonary connection. The extracardiac approach remains popular because it eliminates the need for aortic cross-clamping,...

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