ABSTRACT: Background. The long-term prognosis of diabetic patients with multivessel coronary artery disease (CAD) treated by surgical or percutaneous coronary revascularization is significantly worse as compared to non-diabetics. Lower rates of complete revascularization may be one factor that influences the poor long-term outcome in the diabetic population. Our study assessed the impact of complete revascularization on the long-term prognosis in diabetic patients with CAD treated by percutaneous coronary intervention (PCI). The study included 658 consecutive diabetic patients (m... continue reading about Percutaneous Coronary Interventions in Diabetic Patients: Is Complete Revascularization Important?
ABSTRACT: This study evaluated specially designed perfluorocarbon (PFC) emulsions as blood substitutes in case of induced ischemia of the left heart ventricle in healthy farm pigs. Two hundred milliliters of perfluorocarbon emulsion were infused while 200 ml of blood were simultaneously drawn. Radiographic contrast media were given to aid placement of balloon catheters in the left coronary artery. Histopathological analysis showed that right heart failure caused the deaths of both pigs. Particles (up to > 3 µm) of foreign body materials obstructed capillaries of all organs analyzed (he... continue reading about Interaction Between a Perfluorocarbon Emulsion and Radiographic Contrast Media
The use of stents during percutaneous coronary intervention is now increasingly common. Stent embolization into the systemic or coronary circulation before deployment is a rare but recognized complication of coronary stenting, with hazardous risk for the patient.1–4 Potentially fatal consequences of intracoronary embolization of balloon-mounted stents include coronary thrombosis and subsequent myocardial infarction.5,6 In the past, manual crimping of stents was associated with a significantly increased risk of stent disengagement and embolization. Although manually crim... continue reading about One Stent Lost in Two Arteries
ABSTRACT: The aim of this study was to evaluate the feasibility, safety and efficacy of transcatheter closure of secundum atrial septal defects (ASD) in patients with complex anatomy. From September 1997 to July 2003, a total of 40 patients (median age, 34 years; 65% female) with complex ASDs, defined as the presence of a large defect (stretched diameter > 26 mm) associated with a deficient rim (n = 23); multiple defects (n = 8); a multi-fenestrated septum (n = 5); and defects associated with an aneurysmal septum irrespective of their size (n = 4) underwent closure. The Helex device was... continue reading about Transcatheter Closure of Secundum Atrial Septal Defects with Complex Anatomy (Part I)
Transcatheter closure was successful in the remaining 35 patients (87.5%). The calculated Qp/Qs was 2.5 ± 0.8. All patients had normal to mildly elevated pulmonary artery pressures. The fluoroscopic and total procedure times ranged from 3–63 minutes (median time, 20 minutes) and 20–210 minutes (median time, 90 minutes), respectively. All patients with a single, large defect (n = 19) received an Amplatzer device, ranging in size from 26–38 mm (median, 32 mm; mean... continue reading about Transcatheter Closure of Secundum Atrial Septal Defects with Complex Anatomy (Part II)