Volume 22 - Issue 3 - March, 2010

The Importance of Atrial Pacing during Alcohol Septal Ablation

Case description. A 52-year-old female presented to us with shortness of breath with her daily activities despite optimal medical therapy. An echocardiogram revealed hypertrophic cardiomyopathy with severe dynamic outflow tract obstruction. She was given the options of myectomy and alcohol septal ablation and she chose the latter. On catheterization, a pigtail at the LV apex and a catheter in the aorta revealed a gradient of 235 mmHg (Figure 1, note 400 scale) and a systolic blood pressure of 85 mmHg. As alcohol septal ablation can be complicated by complete heart block, a backup tempo

Incomplete and Inappropriate Coronary Bifurcation Classification

Re: Provisional vs. Complex Stenting Strategy for Coronary Bifurcation Lesions: Meta-Analysis of Randomized Trials

The use of incomplete and inappropriate Medina coronary bifurcation classification has led to major flaws in randomized clinical trials of coronary bifurcation interventions

Dear Editor:
With great interest we read the recently published manuscript entitled: “Provisional vs. complex stenting strategy for coronary bifurcation lesions: meta-analysis of randomized trials.”1 In this meta-analysis, the authors concluded that provisional stenting is a

ST-segment Elevation Myocardial Infarction in Severe Coronary Artery Stenosis: A Case Series

ABSTRACT: Recently, it has been reported that acute ST-segment elevation myocardial infarction (STEMI) frequently develops at the site of severe stenosis. This impression was derived from the observation of stenosis severity after aspiration of the thrombus leading to the event. In the past, STEMI was considered as a thrombotic event on a non-flow limiting coronary plaque mainly. We report a case series of patients who developed STEMI within hours to days of initial angiography, all of whom demonstrated severe flow limiting coronary artery stenosis.



The Impella 2.5 L for Percutaneous Mechanical Circulatory Support in Severe Humoral Allograft Rejection

ABSTRACT: Heart transplant recipients who experience humoral rejection are at risk for hemodynamic instability. We report a case of a 64-year-old male with cardiogenic shock due to allograft rejection requiring mechanical support while undergoing intense immunosuppression. He underwent implantation of a micro-axial endovascular pump (Impella). To our knowledge, this is the first reported case of successful Impella device deployment as a bridge-to-recovery strategy.


Acute allograft rejection is associated with increased morbidity and mortality i

Left Ventricular Pseudoaneurysm Found after Mitral Valve Replacement Performed 30 Years Earlier

ABSTRACT: Pseudoaneurysm of the left ventricle (LV) is a rare cardiac disease that occurs after myocardial infarction or cardiac surgery. Because patients frequently present with nonspecific symptoms, a high index of suspicion is needed to make the diagnosis. This report describes an unusual case demonstrating a large LV pseudoaneurysm after mitral valve replacement performed 30 years earlier.


Case Report. Pseudoaneurysm of the left ventricle (LV) is a rare cardiac disease that occurs after myocardial infarction or cardiac surgery.

Efficacy and Safety of Bivalirudin in Patients with Diabetes Mellitus (Full title below)

Efficacy and Safety of Bivalirudin in Patients with Diabetes Mellitus Undergoing Percutaneous Coronary Intervention in Current Clinical Practice

ABSTRACT: Objectives. This study sought to evaluate the short- and long-term efficacy and safety of bivalirudin in diabetic patients undergoing percutaneous coronary intervention (PCI) in contemporary clinical practice. Background. Early trials of platelet glycoprotein (GP) IIb/IIIa inhibitors have suggested a survival benefit in diabetic patients undergoing PCI. More recently, randomized trials have demonstrated that diabetic patients hav

Stitched To the Heart – Till Intervention Do Us Part

ABSTRACT: The case report describes the situation where a venous infusion catheter was inadvertently stitched to the lateral wall of the right atrium during valve replacement. A dual percutaneous approach was used to first sever the catheter at the suture and then remove both ends safely. The risk of tearing the suture which would have resulted in tamponade had to be avoided.


Entrapment of a central venous catheter to an intracardiac structure in open heart surgery is a rare but serious complication. We report a case wherein a central venous c

Anticoagulation during Percutaneous Coronary Intervention in Diabetics — Is Simpler Always Better?

Bivalirudin is theoretically a promising alternative to unfractionated heparin (UFH). It is a direct thrombin inhibitor and has the ability to block circulating and clot-bound thrombin and prevent thrombin-mediated platelet activation.1 Glycoprotein IIb/IIIa inhibitors (GPI), such as the selective antibody abciximab or the small molecules tirofiban and eptifibatide on the other hand, are not alternatives to heparin but can, in addition to UFH, inhibit platelet aggregation by directly blocking their GPIIb/IIIa receptor. Either of these two strategies is used during most percutaneous coronary pr

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