Volume 15 - Issue 2 - February, 2003

Transcatheter Closure of Patent Ductus Arteriosus in Chinese Adults: Immediate and Long-term Results

Patent ductus arteriosus (PDA) is a common congenital cardiac anomaly. Depending on the size of the PDA, patients may be asymptomatic or in heart failure. Treatment is recommended because of the risk of infective endocarditis and congestive heart failure in the long term. The traditional treatment approach is surgical ligation under direct vision. However, surgical approach is invasive and associated with morbidity. In the past decade, transcatheter closure of PDA has been established as a safe and effective treatment alternative.1–5 The transcatheter approach is less invasive, associated wi



The Prognostic Value of QT Dispersion in Patients Presenting with Acute Neurological Events

QT dispersion (QTD), the difference between the maximum and minimum QT interval on the 12-lead electrocardiogram (ECG), is a marker of heterogeneity of ventricular repolarization.1 Previous studies have shown increased QTD to be a predictor of adverse outcomes in various cardiac disease states. Increased QTD has been found to be associated with cardiac arrhythmias and sudden cardiac death in patients with myocardial infarction, left ventricular hypertrophy, congestive heart failure, coronary artery disease, diabetes and end-stage renal disease.2–10 Acute brain injury has been shown to result



Impact of Gender on the Incidence and Outcome of Contrast-Induced Nephropathy After Percutaneous Coronary Intervention

Contrast-induced nephropathy (CIN) may occur after percutaneous coronary interventions (PCI), particularly in patients with baseline chronic renal failure (CRF) and diabetes mellitus.1–3 We have reported on the adverse impact of CIN post-PCI in patients with CRF (creatinine rise of at least 25% from baseline within 48 hours after PCI).4 In the present study, we analyzed the impact of gender on development and outcome of CIN in a large cohort of PCI patients (with or without CRF).

Methods

Patient population. From a total of 8,628 consecutive patients undergoing PCI (angioplasty,



The Smaller They Come

Percutaneous coronary angioplasty (currently summarized under the term PCI) started 25 years ago with roughly 10 French (Fr) guiding catheters that left no room for contrast medium injection. The actual angioplasty gear (ballon catheter with or without stent) has been miniaturized considerably more than the guiding catheters, which in many centers, still are 7 French. The gained space for contrast medium injection, in conjunction with the advent of digital angiography, has relegated difficult visualization to the non-issues.
Do we take full advantage of this development in favor of the patie



A Novel Percutaneous Technique for Accessing the Normal Pericardium: A Single-Center Successful Experience of 53 Porcine Procedu

The pericardium is a two-layered fibro-serous sac that encloses the heart and the roots of the great vessels. The potential space normally contains only a small amount of fluid, approximately 15–30 ml, comprised mainly of an ultrafiltrate of plasma and possibly some overflow of myocardial interstitial fluid and lymph drainage.1 Recently, emerging data progressively suggested that the normal function of pericardial fluid serves not only to prevent friction from occurring when the heart beats, but perhaps also to provide for a particular biochemical microenvironment that bathes the epicardial



Miniaturization of the Equipment for Percutaneous Coronary Interventions: A Prospective Study in 1,200 Patients

The area of the peripheral puncture site is decreased by 31% with 5 Fr sheaths compared to 6 Fr sheaths (2.2 mm2 vs. 3.1 mm2, respectively), by 49% in comparison with 7 Fr sheaths (4.3 mm2), and by 61% in comparison with 8 Fr sheaths (5.6 mm2). Previously used small guiding catheters (6 Fr and smaller) did not allow stent insertion because of an inner lumen of less than 0.058´´.2–6
New 5 Fr guiding catheters with an inner diameter of 0.058´´ (Z2, Medtronic AVE) allow the use of standard balloon catheters and the insertion of recent commercially available stents with a diameter of



A Randomized Comparison of Direct Stenting Versus Stenting with Predilatation in Native Coronary Artery Disease: Results from th

In the last decade, coronary stenting has evolved from a bailout procedure following balloon angioplasty into an elective strategy for the treatment of all lesions located in vessels with an angiographic reference diameter larger than 3.0 mm.1,2 The standard procedure for stent implantation includes balloon predilatation to facilitate positioning of the stent delivery system at the target lesion; more recently, however, the strategy of stenting without predilatation has become possible due to the availability of new generations of flexible stents, securely crimped on low-profile balloons. This



2002 IAGS Proceedings: Intracranial Interventions (Part I of II)

John Anderson: In the U.S. and in Australia, stroke is the third leading cause of death and the leading cause of disability. Yet despite this, there is an air of therapeutic nihilism about stroke. Patients who present to the emergency room with a stroke are often considered beyond help. Unfortunately, Nick is correct: Where neurologists are with stroke today is essentially where cardiologists were with acute coronary syndromes in 1980, and treatment is not progressing very quickly. General physicians today seem unaware of the fact that things can be done for stroke patients. Unfortunate



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