Volume 27 - Issue 8 - August, 2015

Clinical Relevance of Poststent Fractional Flow Reserve After Drug-Eluting Stent Implantation

Joon-Hyung Doh, MD, PhD1,2;  Chang-Wook Nam, MD, PhD3;  Bon-Kwon Koo, MD, PhD4;  Sung Yun Lee, MD, PhD1; Hyunmin Choi, MD1;  June Namgung, MD, PhD1;  Sung Uk Kwon, MD, PhD1;  Jae-Jin Kwak, MD1; Hyung-Yoon Kim, MD1;  Won-Ho Choi, MD1;  Won Ro Lee, MD, PhD1

The prognostic value of poststent fractional flow reserve (FFR) has not been clearly defined in patients with DES implantation. This study evaluates the association between FFR and clinical outcomes after DES implantation with IVUS assistance....

What Was, What Is, and What Will Be!

Gerald Dorros, MD, ScD 

Dr Dorros warns that in the current health-care climate, cardiologists face the danger of becoming mere technocrats, employed and dictated to by health-care executives, whose main focus is the financial bottom line. Cardiologists must remain determined and focus their efforts on improving and enhancing patient care....

Comparison of Coronary Atherosclerotic Plaque Burden and Composition of Culprit Lesions Between Cigarette Smokers and Non-Smokers by In Vivo Virtual Histology Intravascular Ultrasound

Oluwaseyi Bolorunduro, MD, MPH1;  Colette Cushman, MD2;  Deepak Kapoor, MD2;  Kelsey Alexander, MD2; Jose Cuellar-Silva, MD2;  Smith Giri, MD1;  Vincent Robinson, MD2;  Uzoma N. Ibebuogu, MD1

Published online ahead of print on 2015 May 15

This study investigated the relationship between cigarette smoking and the development of vulnerable coronary artery plaque using virtual histology intravascular ultrasound (VH-IVUS) and showed that cigarette smoking was associated with an increased burden of necrotic core compared with non-smokers. ...

The Correlation Between Cigarette Smoking and Other Risk Factors With Coronary Stenosis Composition

Lloyd W. Klein, MD and Mukesh Gopalakrishnan, MD

The role of traditional risk factors in the production of CAD is well recognized, but only recently have attempts been made to correlate how hypertension, hyperlipidemia, smoking, and diabetes impact stenosis composition and plaque dynamics. By examining the composition of the plaque, we might better appraise its likely behavior and response to various therapies....

Variations in Clinical Presentation, Risk Factors, Treatment, and Prognosis of Spontaneous Coronary Artery Dissection

Adnan Sultan, MD and Rolf P. Kreutz, MD

Spontaneous coronary artery dissection (SCAD) has been considered a rare cause of ACS in younger patients without known cardiovascular risk factors. However, recent studies using advanced imaging modalities indicate a higher incidence of SCAD in patients presenting with ACS than previously thought....

Spontaneous Coronary Artery Dissection: Time for Development of a Large National Registry

Jaya Mallidi, MD, MHS and Gregory R. Giugliano, MD, SM

Spontaneous coronary artery dissection (SCAD) is a complex, life-threatening cardiovascular disease. Given the heterogeneity of the clinical presentation of SCAD and lack of organized data collection, our clinical understanding of this disease remains limited; we propose a concentrated research effort to develop a large-scale, national, multicenter SCAD registry....

The Efficacy and Safety of Antegrade Inoue-Balloon Aortic Valvuloplasty to Treat Calcific Critical Aortic Stenosis

Yoshihito Sakata, MD;  Kenshun Matsubara, MD;  Seiji Tamiya, MD;  Yasufumi Hayama, MD;  Kazutane Usui, MD

A novel PBAV technique for critical aortic stenosis patients with severe calcific degeneration has been developed. The acute therapeutic responses and long-term clinical courses of 405 non-surgical patients were evaluated. ...

Impact of Advanced Age on Procedural and Acute Angiographic Outcomes in Patients Treated for Peripheral Artery Disease With Orbital Atherectomy: A CONFIRM Registries Subanalysis

Michael S. Lee, MD1;  Robert Beasley, MD2;  George L. Adams, MD, MHS3

Data on the outcomes of elderly patients with peripheral arterial disease (PAD) who undergo orbital atherectomy are limited. This analysis compares the procedural and acute angiographic outcomes of PAD patients treated with orbital atherectomy stratified by age (≥75 years of age vs <75 years of age)....

Clinical Outcomes After Percutaneous Coronary Intervention in Acute Myocardial Infarction Due to Unprotected Left Main Coronary Artery Disease

Qing Qin, MD*;  Juying Qian, MD*;  Bing Fan, MD;  Lei Ge, MD;  Junbo Ge, MD

AMI patients with unprotected left main coronary artery as the culprit lesion are a high-risk subgroup with a substantial mortality; PCI has become an option for these patients, but the data are limited. We analyzed the clinical characteristics and the short-term and long-term outcomes of this patient subgroup....

Identification of Risk Factors for Arrhythmia Post Transcatheter Closure of Perimembranous Ventricular Septal Defect

Yifei Li, MD1,2,4*;  Yimin Hua, MD1,2,3*;  Jie Fang, MD5;  Chaomin Wan, MD1,2,3;  Chuan Wang, MD1,2,4;  Kaiyu Zhou, MD1,2,3

Arrhythmias are frequently observed after transcatheter closure of perimembranous ventricular septal defect. Independent risk factors associated with postclosure arrhythmias are still elusive; the current study aimed to identify such risk factors via regression analysis with a long-term follow-up. ...

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