Short-Term Efficacy of Palliative Balloon Aortic Valvuloplasty in Selected Patients with High Operative Risk

Abstract: With the introduction of transcatheter aortic valve implantation (TAVI), the precise role of balloon aortic valvuloplasty (BAV) remains to be established. Methods. Between August 2008 and November 2010, consecutive patients undergoing BAV for severe aortic stenosis (AS) in our center were enrolled. The primary endpoint was survival to hospital discharge. Secondary endpoints were 30-day survival and progression to aortic valve replacement (AVR).



Mechanism of Edge Restenosis After Sirolimus-Eluting Stent Implantation

Abstract: Objectives. The present study evaluated the mechanism of edge restenosis after sirolimus-eluting stent (SES) implantation using serial (post-intervention and follow-up) intravascular ultrasound (IVUS) analysis. Background. There is little information about the mechanism of edge restenosis after SES implantation.



Use of an Objective Tool to Assess Platelet Inhibition Prior to Off-Pump Coronary Surgery to Reduce Blood Usage

Abstract: Background. The current standard of care is to delay coronary surgery 5-7 days after clopidogrel exposure to prevent bleeding complications. We sought to determine the utility of an objective tool (ie, the VerifyNow assay) to measure platelet inhibition (PI) in patients receiving preoperative clopidogrel prior to off-pump coronary artery bypass grafting surgery (OPCABG). Patients and Methods. Between June 2007 and July 2009, a total of 482 isolated OPCABG procedures were performed at our institution.



Effect of Remote Ischemic Preconditioning on Myocardial and Renal Injury: Meta-Analysis of Randomized Controlled Trials

Abstract: Objectives. The purpose of this study was to assess the effect of remote ischemic precondition (RIPC) on the incidence of myocardial and renal injury in patients undergoing cardiovascular interventions as measured by biomarkers. Clinical data were pooled to evaluate the usefulness of RIPC to benefit clinical outcomes. Background. Debate exists regarding the merit of using RIPC for patients undergoing cardiovascular interventions.



Buddy-Balloon Technique for Final Kissing-Balloon Dilatation After Crush Stenting of the Left Main Coronary Artery

Abstract: Background. Crush stenting mandates a final kissing-balloon technique (KBT) for a better clinical outcome; however, recrossing the 2 overlapping stent struts with the balloon catheter is technically challenging. Objectives. The efficacy of the buddy-balloon technique for facilitating completion of the final KBT during crush stenting of the left main coronary artery (LMCA) was evaluated.



Significance of the Invasive Strategy After Acute Myocardial Infarction on Prognosis and Secondary Preventive Medication: A Nationwide Study of 6364 Women and 11,915 Men

Abstract: Objective. To describe gender-specific long-term outcome and initiation of secondary preventive medication among patients with acute myocardial infarction (AMI). Design. Observational cohort study. Setting. Nationwide registries. Patients. We included 18,279 patients: 6364 women (35%) and 11,915 men (65%), admitted with AMI (median age, 67 years; range, 30-90 years) surviving for at least 2 months.



Intravascular Ultrasound Assessment of Postprocedural Incomplete Stent Apposition

Abstract: Background. There has been no detailed intravascular ultrasound (IVUS) analysis to evaluate the degree to which stent underexpansion or reference vessel/stent size mismatch contributes to the occurrence of post-procedural incomplete stent apposition (post-ISA). Methods. We evaluated 238 lesions treated with everolimus-eluting stents (n = 110) or paclitaxel-eluting stents (n = 128).



Effect of Changes in Contractility on Pressure Drop Coefficient and Fractional Flow Reserve in a Porcine Model

Abstract: Objectives and Background. Decisions based on invasive functional diagnostic measurements are often made in the setting of fluctuating hemodynamic variables that may alter resting or hyperemic measurements. The purpose of this investigation is to analyze the effect of myocardial contractility (CY) on invasive functional parameters.



Embolic Protection Device Use and Outcomes in Patients Receiving Saphenous Vein Graft Interventions — A Single-Center Experience

Abstract: Background. Percutaneous treatment of saphenous vein graft disease is hampered by high rates of periprocedural myocardial infarction (MI). The use of embolic protection devices (EPD) during these interventions is a class IB recommendation when technically feasible, yet they are used routinely in less than half of all cases. Our aim was to explore whether or not the under-utilization of EPDs led to any untoward cardiovascular events.



30-Day Outcome After Percutaneous Coronary Angioplasty in Nonagenarians: Feasibility and Specific Considerations in Different Clinical Settings

Abstract: Background. Nonagenarians have been systematically excluded from randomized trials dealing with invasive coronary strategies, resulting in a lack of evidence-based guidelines regarding the optimal approach in this population. Aim. To describe the clinical and procedural characteristics and outcomes of patients 90 years of age or older who were treated with percutaneous coronary interventions (PCI).