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The Official Journal of the International Andreas Gruentzig Society
Friday, May 16, 2008


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Coronary Anomalies

Include more than 35 types that involve the connections between the chambers of the heart, malformed valves or defects in the great vessels. Approximately 1 in 120 infants is born with a coronary anomaly or congenital heart defect, with approximately 1 million people in the U.S. who live with congenital heart defects, and about 4,000 deaths due to these defects in 2001, according to the A.H.A. Some congenital anomalies are genetically-based, while others can be attributed to abnormal chromosomes. Other causes include a mother’s illnesses during pregnancy such as diabetes or rubella, or exposure to certain drugs or alcohol. The types of congenital anomalies, which are present at birth, but not always evident, are as follows: ventricular septal defect, atrial septal defect, patent ductus arteriosus, aortic stenosis, pulmonic stenosis, coarctation of the aorta, atrioventricular canal, tetralogy of Fallot, transposed great vessels, tricuspid atresia, total anomalous pulmonary venous return, truncus arteriosus, hypoplastic left heart hypoplastic right heart and Ebstein’s anomaly.

An Unusual Congenital Coronary Anomaly: Origin of the Left Circumflex Coronary Artery from a Right Coronary Artery Arising from the Left Sinus of Valsalva
ABSTRACT: A 54-year-old male was admitted to our department for stable angina. Coronary angiography and 16-slice computed tomography revealed an abnormal origin of the right coronary artery from the left sinus of Valsalva, coursing between the aorta and the pulmonary trunk and then giving origin to the left circumflex coronary artery. A severe stenosis was present in the middle segment of the right coronary artery, which was successfully treated by stent implantation. J INVASIVE CARDIOL 2007;19:E185?E187



Anomalous Coronary Artery Arising From the Opposite Sinus: Descriptive Features and Pathophysiologic Mechanisms, as Documented by Intravascular Ultrasonography
Background. Anomalous coronary artery originating from the opposite sinus of Valsalva (ACAOS) can cause syncope, myocardial infarction, and sudden death in the absence of critical, fixed stenosis. In the following cases, intravascular ultrasonography (IVUS) was used to document the functional anatomy in ACAOS. This application has not been previously reported in the literature. Methods and Results. In four patients with symptomatic ACAOS and IVUS, the anomalous vessels had a tangential proximal course, and a proximal intramural tract of variable length had fixed lateral compression that worsened during systole. By pressure wire, no significant gradient was present at baseline or after adenosine administration. Ergonovine provocation elicited no spasticity of proximal ectopic segments. Dobutamine, atropine, and rapid saline infusion provoked no symptoms or angiographic changes but did provoke subtle IVUS changes. To correlate these changes with the prognosis, further longitudinal evaluation, involving larger series, will be required. Conclusion. IVUS and pressure-wire methods may be valuable for subclassifying ACAOS and other coronary anomalies in terms of their pathophysiologic repercussions and for substantiating individual indications for treatment. To establish definitive recommendations and protocols, a larger study will be required.



Single Coronary Artery from Right Aortic Sinus with Septal Course of Left Anterior Descending Artery and Left circumflex Artery as Continuation of Right Coronary Artery: A Hitherto Unreported Coronary Anomaly
ABSTRACT: A single coronary artery (SCA) in the absence of structural heart disease is a rare coronary anomaly and is often detected incidentally during coronary angiography. We report a hitherto undescribed type of SCA originating from the right sinus of Valsalva, with the left anterior descending artery having a septal course and the right coronary artery continuing as the left circumflex artery, which was incidentally detected in a 73-year-old female.



An Anomalous Left Coronary Artery Originating from the Pulmonary Artery in a 72-Year-Old Woman: Diagnosis by Color Flow Myocardial Blush and Coronary Arteriography
An anomalous left coronary artery originating from the pulmonary artery (ALCAPA) is a rare congenital coronary abnormality often associated with myocardial infarction, congestive heart failure and sudden death. Survival to adulthood in individuals with this coronary anomaly is quite uncommon. Since mortality approaches 90% in infancy with untreated ALCAPA, early recognition and surgical correction are essential. Using both echocardiographic myocardial blush and coronary arteriography, we describe the new diagnosis of uncorrected ALCAPA in a 72-year-old woman and review contemporary methods for the diagnosis and management of this particular coronary anomaly.



Morphological and Functional Assessment of the Septal Course of a Left Coronary Artery Originating from the Right Sinus of Valsalva in a Heart Transplant Patient
A septal course of the left main coronary artery originating from the right sinus of Valsalva is a rare coronary anomaly of unknown clinical significance. We report on the morphological and functional assessment of this coronary anomaly detected incidentally in a 53-year-old asymptomatic man after orthotopic heart transplantation.



Silent Single Coronary Artery Anomaly Depicted by Magnetic Resonance Angiography
Coronary artery anomalies are rare and usually benign. They are detected by coronary angiograms during invasive catheterization. Single coronary artery anomaly, with the left main artery originating from the proximal right coronary artery, can be responsible for myocardial blood supply insufficiency and causes chest pain or sudden death, especially during physical exercise, as it courses between the aorta and the pulmonary artery. We report a case of a fortuitous diagnosis of single coronary artery anomaly discovered during coronary angiogram and investigated in addition with magnetic resonance angiography. Magnetic resonance imaging can provide a precise description of the coronary artery anomaly and its course between great arteries, allowing accurate surgical planning.



Anomalous Origin of the Left Circumflex Coronary Artery from the Right Coronary Artery and the Left Anterior Descending Artery from the Right Coronary Sinus
We present the case of a 67-year-old female who was admitted to our institution because of anginal chest pain. Selective coronary angiography revealed separate ostial origins of the left anterior descending (LAD) artery and the right coronary artery (RCA) from the right coronary sinus (RCS). The left circumflex (LCx) coronary artery arose from the proximal RCA. The left anterior descending had an anterior free wall and the LCx had a retroaortic course. To our knowledge, this type of combination of anatomical variation of coronary circulation has not been described in the literature. J INVASIVE CARDIOL 2006;18:E214?E216



Bland-White-Garland Syndrome: Not just a Pediatric Coronary Anomaly?
- Richard J. Gumina, MD, PhD, Mark J. Callahan, MD, Joseph G. Murphy, MD Case Report. Echocardiography demonstrated mild global left ventricular hypokinesia without regional wall motion abnormalities, severe leftFigure 1. Right coronary angiography demonstrating collateral circulation to the left coronary system that arises from the pulmonary artery. Coronary angiography revealed a large right-dominant coronary artery that filled the entire left ...



Single Coronary Artery with the Absence of a Left Anterior Descending Artery
Anomalous origin of coronary arteries is discovered incidentally during coronary arteriography or at autopsy, and awareness among angiographers is required. We describe a case with a rare combination of a single coronary artery originating from the right sinus of Valsalva associated with an absent left anterior descending artery and a secundum-type atrial septal defect.



Anomalous Origin of the Left Coronary Artery from the Right Coronary Artery: A Rare Case of a Single Coronary Artery Originating from the Right Sinus of Valsalva in a Man with Suspected Coronary Artery Disease
Anomalous Origin of the Left Coronary Artery from the Right Coronary Artery: A Rare Case of a Single Coronary Artery Originating from the Right Sinus of Valsalva in a Man with Suspected Coronary Artery Disease CASE REPORTS: Anomalous Origin of the Left Coronary Artery from the Right Coronary Artery: A Rare Case of a Single Coronary Artery Originating from the Right Sinus of Valsalva in a Man with Suspected Coronary Artery Disease - Amgad N. Makaryus, James Orlando, Stanley Katz &...



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