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CLINICAL EVENTS CALENDAR

Non-Accredited Education

CLINICAL EXPERIENCE WITH A NEW HYBRID CORONARY WIRE
On Demand Web ArchiveNon-Accredited
Target Audience: Physicians, nurses, and technologists.
This activity is supported by an educational grant from Terumo Medical Corporation.

CASE REPORTS

Successful Percutaneous Closure of an Aortic Graft Pseudo- Aneurysm with a Patent Foramen Ovale Occluder Device

Subtraction angiograms of the descending thoracic aorta. ( A) Nonselective anterior-posterior angiogram with a pigtail catheter demonstrates the pseudo-aneurysm (arrow). ( B) Selective right anterior oblique angiogram with a Judkins right (JR) 4 catheterRight anterior oblique fluoroscopy of the descending thoracic aorta. (A) Both the distal limb (arrow) and the proximal limb (dashed arrow) of the device are deployed but not released from the delivery catheter and no tension is exerted. The arrowhead is tTransesophageal echocardiography was performed during the procedure. ( A) Transverse images (0 degrees) of the lumen of the descending thoracic aorta (*), the area of blood and thrombus (§), and the focal defect (arrow) of the echogenic walls of the aortiCT pre- and post-device placement. (A) Contrast study predevice placement depicting the descending thoracic aortic lumen (*), contrast within the contained pseudo-aneurysm (arrow), and a large area (‡) of blood and thrombus now walled off from the pseudo-Non-contrasted CT obtained 34 months after device placement demonstrates resolution of the pseudoaneurysm with stable placement of the device within the aorta.(A) Maximal intensity projection (MIP) CT of the thoracic aorta after device implantation. The white arrow demonstrates the distal limb of the device and the red arrow demonstrates the outline of proximal limb of the device. No contrast is noted in the ps



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

Case Report. A 22-year-old female presented to an outside hospital with back pain radiating to the epigastrum. The patient had a history of hypertension and Takayasu’s arteritis. At age 17 she underwent resection of an ascending aortic aneurysm via a median sternotomy with placement of a graft to the aortic arch and banding of the sino-tubular junction because of significant aortic regurgitation. Six weeks prior to her presentation with back pain, the patient underwent resection of a descending thoracic aortic aneurysm via a left posterior-lateral thoracotomy and placement of a 26 mm graft. This included resection of a portion of the aortic arch (hemi-arch) to the descending thoracic aorta just cranial to the diaphragm.



Stabilization of Renal Function, Improvement in Blood Pressure Control and Pulmonary Edema Symptoms after Opening a Totally Oc

Abdominal aortogram showing total occlusion of the left
renal artery with faint late filling of a vascular structure (arrows) at
site of left renal artery.MRI of the kidneys (A) showed a normal sized right kidney (R arrows) and left kidney atrophy (L arrows) measuring (B) 10.5
and 8.4 cm, respectively, with severe left renal arteries stenosis.Renal revascularization.
( A) A 6 Fr
RDC guide (Cordis
Corp.) was used to
engage left renal and
angiography showed total
occlusion (arrows). ( B)
The lesion was crossed
with Choice PT XS
(Boston Scientific Corp.)
wire and distal contrast
injection throughFollowing left renal revascularization, angiography showed
filling of a capsular collateral (arrows) which provided renal perfusion
during occlusion.R e n a l
nuclide scintigraphy.
RK = right kidney,
LK = left kidney, B =
bladder. Following
intravenous injection
of MAG3 labeled
with technetium-99m,
flow phase images
were attained for one
minute. Images were
obtained for an additional
20 minutes
(Left



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

Stenting has emerged as a procedure associated with low mortality and morbidity for symptomatic renovascular disease. Frequently responsible for uncontrollable hypertension, congestive heart failure and progressive renal failure leading to endstage renal disease, it is prevalent among elderly patients.1 Acute pulmonary edema is not an infrequent presentation of severe renovascular disease in the elderly,2 and carries high risk in patients will diminished cardiopulmonary reserve. In most cases, total occlusion of a renal artery supplying a small atrophied kidney has not be



Challenging Closure of a Patent Foramen Ovale via a Superior Approach

(A) Balloon sizing of the patent foramen ovale (PFO) in the
AP projection, with localization of the PFO (arrow) and illustration of
distorted anatomy. (B) Deployment of the Amplatzer device (arrow).
(C) Right atrial injection showing the Amplatzer device



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

This case describes the closure of a patent foramen ovale (PFO) via the right internal jugular (IJ) vein in a young patient with an interrupted inferior vena cava (IVC) awaiting liver transplantation.
Case Report. A 25-year-old male with chronic liver failure due to Budd Chiari syndrome had a PFO discovered on contrast echocardiography as part of his transplantation workup. He was subsequently referred by the transplant team for PFO closure prior to liver transplantation to avoid the potential for intraoperative paradoxical embolism.
As the IVC was known to be



Percutaneous Mitral Commissurotomy in a Case of Mirror-Image Dextrocardia and Rheumatic Mitral Stenosis

Chest skiagram in a postero-anterior view suggesting situs
inversus and dextrocardia.Frontal view of the heart with the pigtail catheter in the aortic
root and MPA catheter in the pulmonary artery, consistent with
mirror-image dextrocardia.Levophase pulmonary angiography in pseudo-AP
and left lateral views delineating the interatrial septum (white arrow)
with prominent atrial septal aneurysm and aortic root.Levophase pulmonary angiography in pseudo-AP
and left lateral views delineating the interatrial septum (white arrow)
with prominent atrial septal aneurysm and aortic root.Transseptal puncture in a left lateral view. Contrast was
injected into the cavity of the left atrium through the needle across the
interatrial septum. Contrast staining of the interatrial septum is
marked with a white arrow. A pigtail catheter is placFully-expanded Accure balloon across the mitral valve,
with the reverse loop in the left atrium.



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

Distorted cardiac anatomy offers technical difficulties during fluoroscopy-guided transcatheter procedures. This is even more the case with percutaneous transvenous mitral commissurotomy (PTMC), where the cardiac malpositions considerably increase the complications involved in interatrial septal puncture and left ventricular entry. Though it has been established as the procedure of choice in a selected subset of patients with rheumatic mitral stenosis (MS), there are only a few reports on successful PTMC in altered cardiac anatomy using the standard Inoue technique.1–6 Here



A Case of Acute Coronary Thrombosis in Diffuse Coronary Artery Ectasia

Diffuse coronary artery ectasia with acutely occluded
right coronary artery ( A )Figure 1. Diffuse coronary artery ectasia with acutely occluded
right coronary artery ( A ), and thrombotic material in the circumflex
artery ( B ).Patent right coronary artery (RCA) and 3 large thrombi in
distal RCA (marking of deflated balloon visible). A 4.0 x 15 mm
bare-metal stent was successfully deployed in its midcourse.Angiogram 6 days after initial treatment, showed decreased
size of intracoronary thrombi after therapy with glycoprotein IIb/IIIa
inhibitor and low-molecular heparin.



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

Case Report. A 75-year-old Afro-Caribbean male presented to our hospital with typical ischemic chest pain associat ed wi th a rai sed t roponin I l eve l of 3.5. His electrocardiogram (ECG) on admission showed anterolateral T-wave inversion. The diagnosis of non-ST-elevat ion myocardial infarction (NSTEMI) was made. He was treated with nitrates, low-molecular weight heparin, aspirin and clopidogrel. Past medical history included a previous non-Qwave inferior MI in 1994. He had no history of significant childhood fever.
Coronary angiography in 1994 showed



Percutaneous Coronary Revascularization of an Occluded Ostial Circumflex Artery Arising from the Right Coronary Cusp Utilizing

Right anterior oblique fluoroscopic projection showing the
right coronary artery and epicardial collateral retrograde filling of the
left circumflex artery.Asahi Prowater Flex wired antegrade through the right
coronary artery into the left circumflex artery via a retrograde
epicardial collateral.Distal portion of the 300 cm Asahi Prowater Flex wire in
the right subclavian artery via a retrograde passage through the left circumflex artery.Left anterior oblique fluoroscopic projection of aortic
angiography demonstrating an anomalous left circumflex ostium originating
from right coronary cusp with an intraluminal wire.Final angiographic result showing anterograde filling of the
anomalous left circumflex artery.Left anterior oblique fluoroscopic projection showing the left
anterior descending artery without the left main or left circumflex
arteries visible.



VOLUME: 20 PUBLICATION DATE: Jan 24 2008
Issue Number: 
1 (Jan 2008)

Approximately 30% of patients with significant coronary artery disease (CAD) have a chronically occluded vessel ( CTO).1 Due to frequent difficulty in crossing the CTO lesion by standard wire techniques, novel approaches have been created to improve success rates. One such innovative strategy is to cross the lesion in a retrograde approach utilizing collateral vessels.
This approach was born out of the peripheral angioplasty experience that frequently demonstrated success in crossing CTOs in a distal-to-proximal lesion progression, consistent with the histological realizati



Successful Recanalization of In-Stent Coronary Chronic Total Occlusion by Subintimal Tracking

Figure 1. Images of the right coronary artery before (A)A guidewire with
the Progreat microcatheter
was passed subintimally along
the outside of the original
stent and re-entered the distal
true lumen (B–D). The final
images of the RCA after
placement of several Cypher™
stents (E–F). The final
images of the RCA after
placement of several Cypher™
stents (E–F).Follow-up
angiogram 5 months after reintervention
(G–H).Follow-up
angiogram 5 months after reintervention
(G–H).Figure 3. Intravascular ultrasound (IVUS) images from the posterior descending artery to
the mid RCA after guidewire passage and predilatation. The IVUS catheter is placed in the
distal true lumen. The posterolateral branch is seen at the 11 o’clock pos(B). The IVUS catheter is placed in the subintimal space. The occluded original stent is seen
at the 9–12 o’clock position(C). The IVUS catheter is now seen in the original stent lumen
at the proximal portion of the occlusion site (D)(C). The IVUS catheter is now seen in the original stent lumen
at the proximal portion of the occlusion site (D)Figure 4. Final intravsacular images from the posterior descending
artery to the mid RCA. The new stent is placed at the posterior
descending artery. The posterolateral branch is emerging at the 11–12
o’clock position (A). The new stent is placed in the subintimal space.
The crushed original stent is seen at the 3–5 o’clock position (double
arrows), and an extraluminal hematoma is observed at the 12–2
o’clock position (single arrow) (B)The new stent is placed in the
subintimal space. The crushed original stent is seen at the 12–2
o’clock position (double arrow), and the extraluminal hematoma is
observed at the 9–12 o’clock position (single arrow) (C) The new
stent is now placed in the original stent at the proximal portion of the
occlusion site (D).and after (B) the placement
of several stents 1 year before the index procedure.
A guidewire with
the Progreat microcatheter
was passed subintimally along
the outside of the original
stent and re-entered the distal
true lumen (B–D).A guidewire with
the Progreat microcatheter
was passed subintimally along
the outside of the original
stent and re-entered the distal
true lumen (B–D).Figure 2. A diagnostic image
of the right coronary artery
(RCA) shows focal in-stent
restenosis at the proximal
RCA and a totally occluded
stent from the mid-to-distal
RCA (A).



VOLUME: 20 PUBLICATION DATE: Apr 01 2008
Issue Number: 
4 (April 2008)

Percutaneous treatment of coronary chronic total occlusions (CTO) remains one of the major challenges in interventional cardiology. Although CTO in the form of in-stent restenosis (ISR-CTO) is relatively rare, with an incidence of 1.6% of stent procedures, it is associated with significant morbidity.1 The paucity of published data on this rare population indicates that the low success rate of PCI is mostly due to difficulty in passing the guidewire across the occlusive stent lumen.1,2 Thus far, there is no consensus on the best method to overcome the failure of w



Collateral Circulation via a Rare, Anomalously Arising Right Ventricular Branch

Figure 1. Chronic total occlusion of the proximal right coronary
artery (RCA).Figure 2. Right ventricular (RV) branch arising directly from the
aorta and providing collateral supply to the occluded right coronary
artery (RCA).



VOLUME: 20 PUBLICATION DATE: Apr 01 2008
Issue Number: 
4 (April 2008)

Coronary collateral vessels are able to supply blood to a myocardial territory vascularized by severely stenosed or occluded epicardial arteries. They may contribute significantly to the limitation of ischemia and infarct size.1,2 Improvement in left ventricular function3,4 and prevention of left ventricular aneurysm formation5 also has been attributed to the presence of collateral vessels.
Variations in coronary anatomy are not uncommon. They are usually benign, but can be a cause of confusion to the angiographer and have no clinical significanc



Percutaneous Coronary Intervention in Neurosurgical Patients

Figure 1A. Coronary angiography in a 44-year-old female with
NSTEMI and a history of intracranial aneurysm with subarachnoid
hemorrhage. There is a thrombotic lesion of the mid left anterior
descending artery.Figure 1B. Coronary angiography after stenting of the culprit lesion
on bivalirudin. There is new thrombus proximal to the treated lesion.Figure 1C. Coronary angiography after addition of eptifibatide and
placement of a second stent with a good angiographic result.



VOLUME: 20 PUBLICATION DATE: Apr 01 2008
Issue Number: 
4 (April 2008)

The management of coronary disease in patients with spinal or intracranial disease may be challenging. In some cases, coronary lesions may require treatment before neurosurgery, while in others, myocardial ischemia or infarction may occur in the postoperative patient or simultaneously with stroke or intracranial hemorrhage. Patients with subarachnoid and intracranial hemorrhage have a high incidence of cardiovascular complications,1 and antiplatelet and anticoagulant medications normally used in coronary disease may further increase the risk of hemorrhage.2 Recent neur



Hemodynamics “Au Contraire” Despite Diastolic Flow Reversal and Angiographically Severe Aortic Regurgitation

Pressure half-time obtained on follow-up transthoracic
echocardiography (heart rate: 60 bpm).Left-heart hemodynamics of central aortic and femoral
pressures.Right-heart catheterization depicting wedge pressure.Left-heart hemodynamics depicting left ventricular enddiastolic
pressure.Left-heart hemodynamics showing central aortic and left
ventricular pressures.



VOLUME: 20 PUBLICATION DATE: Jun 01 2008
Issue Number: 
6 (June 2008)

Aortic regurgitation (AR) is characterized by inadequate aortic valve closure that results in the reflux of blood from the aorta into the left ventricle (LV) during diastole. Assessment of the degree of regurgitation is paramount to clinical decision-making in patients with AR, because patients with severe AR most often require surgical intervention. Semiquantitative grading of AR with color and spectral Doppler echocardiography or with angiography is widely used, but both techniques are hindered by significant limitations. Furthermore, quantitative parameters such as regurgitant volume and




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Newly Revised and Updated for 2009!

practical EP



Press Release


FDA Clears Invatec's Mo.Ma Ultra Proximal Cerebral Protection Device

— Bethlehem, Pennsylvania – Invatec received 510(k) clearance from the U.S. Food and Drug Administration (FDA) in October to market its Mo.Ma Ultra Proximal Cerebral Protection Device for use during carotid artery stenting (CAS). The device effectively reduces and captures debris released during the stenting procedure to prevent it from traveling to the brain, where it has the potential to cause a stroke.


CME Showcase


The Use of Remote Robotic Navigation
in Complex Arrhythmias

Complimentary Accredited Web Archive
This activity is designed for electrophysiologists and EP allied professionals.

Diagnosing Coronary Artery Disease: Advanced Cardiovascular Imaging Solutions

Complimentary accredited web archive
This activity is intended for physicians, nurses, and technologists.



New Standards of Care for CRMD Antibiotic Protection
Complimentary CME Accredited Webcast
Dates: November 18, 2008 Time: 6:00 pm ET November 19, 2008 Time: 3:00 pm ET
This activity is sponsored by the North American Center for Continuing Medical Education.

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