From the Journal

Comparison of Provisional 1-Stent and 2-Stent Strategies in Diabetic Patients With True Bifurcation Lesions: The EES Bifurcation Study

Omar A. Meelu, MS1;  Matthew I. Tomey, MD1;  Samantha Sartori, PhD1;  Nisharahmed Kherada, MD1; Marco G. Mennuni, MD1,2;  Kleanthis N. Theodoropoulos, MD1;  Swapna Sayeneni, MBBS1; Usman Baber, MD1;  Robert T. Pyo, MD1;  Jason C. Kovacic, MD, PhD1;  Pedro Moreno, MD1;  Prakash Krishnan, MD1; Roxana Mehran, MD1;  George D. Dangas, MD, PhD1;  Annapoorna S. Kini, MD1;  Samin K. Sharma, MD1

Diabetes mellitus is associated with greater atherosclerotic burden and higher incidence of bifurcation lesions, and unfavorable outcomes after PCI. In this series of diabetic patients undergoing complex bifurcation PCI using everolimus-eluting stent implantation, there was no difference between 1-stent and 2-stent strategies with respect to ischemic events at 1 year....

Risk of Developing Coronary Artery Disease Following a Normal Coronary Angiogram in Middle-Aged Adults

Maheswara S.G. Rao Golla, MBBS1;  Timir Paul, MD2;  Siddhartha Rao, MD1; Chris Wiesen, PhD3;  Michael Yeung, MD1;  George A. Stouffer, MD1

It is unknown whether coronary angiography in middle-aged adults showing no evidence of atherosclerosis identifies individuals at low risk for subsequent development of coronary artery disease (CAD). Even mild atherosclerosis increased the rate of progression of CAD by 10-fold and the rate of revascularization by 8-fold. ...

Treatment of Coronary Bifurcations: Progress and Future

Ganesh Athappan, MD and Samin K. Sharma, MD

The authors provide their thoughts on the current state of bifurcation interventions. Despite the advances in stent technology and catheter techniques, bifurcation lesions present a formidable challenge to the interventional cardiologist because of inferior angiographic results and poor clinical outcomes compared with non-bifurcation lesions....

Three-Year Outcomes of Percutaneous Coronary Intervention With Next-Generation Zotarolimus-Eluting Stents for De Novo Coronary Bifurcation Lesions

Miroslaw Ferenc, MD1;  Ran Kornowski, MD2;  Jorge Belardi, MD3;  Patrick Serruys, MD, PhD4;  Sigmund Silber, MD5;  Petr Widimský, MD6;  Stephan Windecker, MD7;  Franz-Josef Neumann, MD1

We investigate the outcomes of percutaneous coronary intervention (PCI) in bifurcation versus non-bifurcation lesions using the next-generation Resolute zotarolimus-eluting stent. There was an increased risk associated with bifurcation lesions during the first 30 days; beyond 30 days, bifurcation lesions and non-bifurcation lesions yielded similar 3-year outcomes. ...

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