From the Journal

Clinical Impact of Second-Generation Everolimus-Eluting Stents Compared With First-Generation Drug-Eluting Stents in Diabetic Patients Undergoing Multivessel Percutaneous Coronary Intervention

Lakshmana Pendyala, MD;  Joshua Loh, MD;  Hironori Kitabata, MD;  Sa’ar Minha, MD;  Fang Chen, PhD;  Rebecca Torguson, MPH;  William Suddath, MD;  Lowell Satler, MD;  Augusto Pichard, MD;  Ron Waksman, MD

This study aimed to evaluate the safety and efficacy of everolimus-eluting stent (EES) use compared with first-generation drug-eluting stent (DES) use in diabetic patients undergoing multivessel percutaneous coronary intervention. In diabetic patients undergoing native multivessel PCI, the use of EES was associated with superior 1-year safety as compared with use of first-generation DES.  ...

Systematic Review of the BridgePoint System for Crossing Coronary and Peripheral Chronic Total Occlusions

Jedrek Wosik, MD1;  Deborah Shorrock1;  Georgios Christopoulos, MD1;  Anna Kotsia, MD, PhD1;  Bavana V. Rangan, BDS, MPH1;  Michele Roesle, RN1;  Spyros Maragkoydakis, MD2;  Shuaib M. Abdullah, MD1;  Subhash Banerjee, MD1;  Emmanouil S. Brilakis, MD, PhD1

The authors performed a systematic review of the literature on the BridgePoint system published between October 2008 and August 2014 and found the system to be associated with high procedural success rates and low complication rates when used for crossing both coronary and peripheral CTOs....

Utility of Transradial Approach for Peripheral Vascular Interventions

Tejas Patel, MD1,2;  Sanjay Shah, MD1,2;  Samir Pancholy, MD3;  Surender Deora, MD1;  Kintur Sanghvi, MD4; Rajiv Gulati, MD, PhD5;  John Coppola, MD6

This review demonstrates the feasibility of the transradial approach (TRA) to address different peripheral vascular lesions. Advantages and limitations are highlighted, and the results of different studies using this approach for peripheral interventions are discussed.  ...

Percutaneous Paravalvular Leak Closure for Balloon-Expandable Transcatheter Aortic Valve Replacement: A Comparison With Surgical Aortic Valve Replacement Paravalvular Leak Closure

Kazuaki Okuyama, MD;  Hasan Jilaihawi, MD;  Mohammad Kashif, MD;  Vikas Soni, MD;  Takashi Matsumoto, MD; Wen Loong Yeow, MD;  Mamoo Nakamura, MD;  Wen Cheng, MD;  Saibal Kar, MD;  Raj R. Makkar, MD

Paravalvular leak is frequently observed after transcatheter aortic valve replacement (TAVR) and is related to increased mortality. Percutaneous PVL closure has been performed following surgical aortic valve replacement (SAVR); however, the experience in TAVR remains limited. This study compares this technique between post-TAVR and post-SAVR cases. ...

Ahead of Print

A Meta-Analysis of Randomized Controlled Trials of Conventional Stenting Versus Direct Stenting in Patients With Acute Myocardial Infarction

Aiman Alak, MD1;  Peter Lugomirski, MD2;  Natasha Aleksova, MD1;  Sanjit S. Jolly, MD, MSc1

Published online ahead of print on 2015 Jun 15

Direct stenting (DS) is commonly used during percutaneous coronary intervention for acute myocardial infarction (AMI) to prevent distal embolization. We compare DS with conventional stenting (CS) in patients presenting with AMI in a meta-analysis of randomized controlled trials; small trials suggest a potential benefit to DS in AMI.

Transradial Approach for Cardiac Catheterization in Patients With Negative Allen’s Test

Christos Maniotis, MD, PhD1;  Michalis Koutouzis, MD, PhD1;  Constantinos Andreou, MD1;  Evangelos Lazaris, MD1;  Ioannis Tsiafoutis, MD2;  Theodoros Zografos, MD, PhD2;  Klio Chantziara, MD, PhD3;  Savas Nikolidakis, MD1;  Zenon S. Kyriakides, MD, PhD1

Published online ahead of print on 2015 Jun 15

This study assesses the efficacy and safety of the transradial approach regardless of the Allen’s test results for coronary angiography and angioplasty. The transradial approach for coronary angiography and ad hoc angioplasty can be performed with similar efficacy and safety regardless of preprocedural Allen’s test results.

Coronary Artery Bypass Surgery Compared With Percutaneous Coronary Intervention for Proximal Left Anterior Descending Artery Treatment in Patients With Acute Coronary Syndrome: Analysis From the ACUITY Trial

Marco G. Mennuni, MD1;  George D. Dangas, MD, PhD1,2;  Roxana Mehran, MD1,2;  Yanai Ben-Gal, MD3;  Ke Xu, PhD2;  Philippe Généreux, MD2,4,5;  Sorin J. Brener, MD2,6;  Frederick Feit, MD7;  A. Michael Lincoff, MD8;  E. Magnus Ohman, MD9;  Martial Hamon, MD10;  Gregg W. Stone, MD2,4

Published online ahead of print on 2015 Jun 15

This study compares the outcomes of acute coronary syndrome patients with proximal LAD culprit lesions receiving PCI vs CABG, and found that an initial revascularization strategy of PCI compared with CABG yielded similar 1-year death, MI, and MACE rates, although unplanned revascularization was more common after PCI.

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