From the Journal

Correlation Between OCT-Derived Intrastent Dimensions and Fractional Flow Reserve Measurements After Coronary Stent Implantation and Impact on Clinical Outcome

Sebastian Reith, MD1;  Simone Battermann1;  Martin Hellmich, PhD2;  Nikolaus Marx, MD1;  Mathias Burgmaier, MD1

This study investigates the relationship of OCT-derived intrastent lumen dimensions and FFR-derived hemodynamic relevance immediately after stent implantation and evaluates the clinical impact of these parameters at follow-up. Post-stenting FFR and OCT data were compared and related to MACE at follow-up in 66 stable patients with a coronary de novo lesion who had been treated by stent implantation.   ...

Expansion of the Indication of Transcatheter Aortic Valve Implantation — Feasibility and Outcome in “Off-Label” Patients Compared With “On-Label” Patients

Christian Frerker, MD1;  Jury Schewel, MD1;  Dimitry Schewel, MD1;  Peter Wohlmuth2;  Tobias Schmidt, MD1; Felix Kreidel, MD1;  Ralf Bader, MD3;  Karl-Heinz Kuck, MD1;  Ulrich Schäfer, MD1

This study compares both the feasibility and outcomes of “off-label” transcatheter aortic valve replacement (TAVR) patients (n=156) with a standard “on-label” TAVR population (n=435) at a single institution. ...

Sheathless Guide Catheter Coronary Intervention Via Radial Artery: Single-Center Experience With 9658 Procedures

Norio Tada, MD1;  Kaname Takizawa, MD1;  Mitsuru Kahata, MD1;  Masataka Taguri, PhD2; Tatsushi Ootomo, MD1;  Naoto Inoue, MD1 

We conducted a retrospective investigation of all TRIs performed at Sendai Kousei Hospital from January 2004 to December 2013 to evaluate the efficacy and safety of sheathless TRI in a large population (n=9658)....

The Safety and Efficacy of Peripheral Vascular Procedures Performed in the Outpatient Setting

Peyman Mesbah Oskui, MD1,2;  Robert A. Kloner, MD, PhD2,4;  Steven Burstein, MD3,5,8;  Katrine Zhiroff, MD3,8;  Benjamin Richard Kartub6;  Christina Economides, MD3,8;  Jenny Brook, MS7;  Guy S. Mayeda, MD3,5,8

Peripheral vascular interventions have been traditionally performed in the inpatient setting. We evaluate the safety and efficacy of peripheral vascular interventions performed in a private outpatient catheterization laboratory by performing a retrospective chart review of the first 500 consecutive procedures that were performed at our lab from February 2012 through February 2013....

Ahead of Print

Myocardial Bridging: An Up-to-Date Review

Michael S. Lee, MD and Cheng-Han Chen, MD

Published online ahead of print on 2015 May 15

Myocardial bridging is a congenital anomaly in which a segment of a coronary artery takes a “tunneled” intramuscular course under a “bridge” of overlying myocardium. This review discusses the morphology, histology, pathophysiology, prognosis, and various treatment modalities.

The Left Main Bifurcation Angle and Changes Throughout the Cardiac Cycle: Quantitative Implications for Left Main Bifurcation Stenting and Stents

Chauncy B. Handran, MD1;  Ross F. Garberich, MD1;  John R. Lesser, MD1; Timothy D. Henry, MD1;  Michael Gilmore2;  Robert B. Schwartz, MD1

Published online ahead of print on 2015 May 15

Left main (LM) stenting is an accepted alternative to coronary artery bypass grafting. However, the LM bifurcation has great anatomic variability. The objective of this study was to quantify the LM bifurcation angles and their changes throughout the cardiac cycle using coronary computed tomography angiography. 

Impact of Chronic Statin Therapy on Postprocedural Contrast-Induced Nephropathy in Patients Undergoing Non-Emergent Percutaneous Coronary Intervention

Jake M. Chanin, MD, MSc*;  David C. Yang, MD*;  Muhammad A. Haider, MD;  Rajesh V. Swaminathan, MD; Luke K. Kim, MD;  Konstantinos Charitakis, MD;  Michael Tanoue, MD;  Robert M. Minutello, MD; Christopher L. Gade, MD;  Harsimran S. Singh, MD;  Geoffrey Bergman, MD; S. Chiu Wong, MD;  Dmitriy N. Feldman, MD

Published online ahead of print on 2015 May 15

Following percutaneous coronary intervention (PCI), elevations in serum creatinine level and declines in glomerular filtration rate are common. Prior studies have demonstrated benefit of chronic statin therapy in the prevention of contrast-induced nephropathy (CIN); however, this study sought to examine whether chronic statin therapy reduces the incidence of CIN in the non-emergent PCI setting. 

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