From the Journal

Recanalization of Infrainguinal Chronic Total Occlusions With the Crosser System: Results of the PATRIOT Trial

John Laird, MD1;  James Joye, DO2;  Naveen Sachdev, MD3;  Paul Huang, MD4;  Ronald Caputo, MD5; Imran Mohiuddin, MD6;  John Runyon, MD7;  Tony Das, MD8

Peripheral artery CTOs are commonly encountered during the evaluation and management of patients with symptomatic peripheral artery disease.  We report the results of a prospective, multicenter trial that evaluated the angiographic and functional outcomes of a recanalization system designed to aid crossing of infrainguinal occlusions....

Serial Intravascular Ultrasound Analysis of Stent Strut Distribution and Fracture: An Integrated Analysis of the Taxus IV, V, and VI Trials

Radoslaw Pracon, MD1;  Maksymilian P. Opolski, MD2;  Gary S. Mintz, MD3;  Jerzy Pregowski, MD4; Mariusz Kruk, MD1;  Jeffrey J. Popma, MD5;  Lazar Mandinov, MD6;  Hong Wang6;  Stephen G. Ellis, MD7; Eberhard Grube, MD8;  Keith D. Dawkins, MD6;  Gregg W. Stone, MD9;  Neil J. Weissman, MD2

Non-uniform distribution of drug-eluting stent struts may cause uneven drug deposition associated with an adverse neointimal response and clinical events. This study assesses circumferential stent strut distribution in bare-metal (BMS, n=117) and paclitaxel-eluting (Taxus, n=125) stents post implantation and at 9-month follow-up, as well as its impact on intimal hyperplasia....

Comparison of the Novel Vasodilator Uridine Triphosphate and Adenosine for the Measurement of Fractional Flow Reserve

Jacob Sivertsen1;  Jan Jensen1,  Søren Galatius1;  Jakob Raunsø1;  Jaya Rosenmeier, MD, PhD2

Our aim was to examine fractional flow reserve responses of intravenous adenosine with increasing doses of intracoronary (IC) adenosine versus IC uridine triphosphate in patients with coronary artery disease. ...

Transcoronary Mapping of Ventricular Asynchrony Due to Left Bundle Branch Block in a Porcine Model

Konstantin M. Heinroth, MD1;  Susanne Unverzagt, PhD1;  Dirk Mahnkopf, MD2;  Alexander Plehn, MD1;  Michael Buerke, MD3;  Karl Werdan, MD1;  Roland Prondzinsky, MD4

Optimal positioning of the left ventricular (LV) lead at the latest activated part of the left ventricle is one of the major challenges in implantation of cardiac resynchronization therapy (CRT) devices with respect to ascertaining an optimal resynchronization effect resulting in a high responder rate. In the present study, we evaluated the feasibility of transcoronary measurement of LV electrical activation by a coated guidewire in a porcine model. ...


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